Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species

Glioblastoma multiforme (GBM) is among the most lethal of human malignancies. Most GBM tumors are refractory to cytotoxic therapies. Glioma stem cells (GSCs) significantly contribute to GBM progression and post-treatment tumor relapse, therefore serving as a key therapeutic target; however, GSCs are...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Alan Mitteer, R., Wang, Yanling, Shah, Jennifer, Gordon, Sherika, Fager, Marcus, Butter, Param-Puneet, Jun Kim, Hyun, Guardiola-Salmeron, Consuelo, Carabe-Fernandez, Alejandro, Fan, Yi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564801/
https://ncbi.nlm.nih.gov/pubmed/26354413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13961
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