Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining

The ongoing evolution of Ebolaviruses poses significant challenges to the development of immunodiagnostics for detecting emergent viral variants. There is a critical need for the discovery of monoclonal antibodies with distinct affinities and specificities for different Ebolaviruses. We developed an...

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Publicado no:Sci Rep
Main Authors: Wang, Bo, Kluwe, Christien A., Lungu, Oana I., DeKosky, Brandon J., Kerr, Scott A., Johnson, Erik L., Jung, Jiwon, Rezigh, Alec B., Carroll, Sean M., Reyes, Ann N., Bentz, Janelle R., Villanueva, Itamar, Altman, Amy L., Davey, Robert A., Ellington, Andrew D., Georgiou, George
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564727/
https://ncbi.nlm.nih.gov/pubmed/26355042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13926
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