Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining

The ongoing evolution of Ebolaviruses poses significant challenges to the development of immunodiagnostics for detecting emergent viral variants. There is a critical need for the discovery of monoclonal antibodies with distinct affinities and specificities for different Ebolaviruses. We developed an...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Bo, Kluwe, Christien A., Lungu, Oana I., DeKosky, Brandon J., Kerr, Scott A., Johnson, Erik L., Jung, Jiwon, Rezigh, Alec B., Carroll, Sean M., Reyes, Ann N., Bentz, Janelle R., Villanueva, Itamar, Altman, Amy L., Davey, Robert A., Ellington, Andrew D., Georgiou, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564727/
https://ncbi.nlm.nih.gov/pubmed/26355042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13926
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