Preclinical Development of Inactivated Rabies Virus–Based Polyvalent Vaccine Against Rabies and Filoviruses

We previously described the generation of a novel Ebola virus (EBOV) vaccine based on inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) incorporated in the RABV virion. Our results demonstrated safety, immunogenicity, and protective efficacy in mice and nonhuman primates (NHPs). Prot...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Willet, Mallory, Kurup, Drishya, Papaneri, Amy, Wirblich, Christoph, Hooper, Jay W., Kwilas, Steve A., Keshwara, Rohan, Hudacek, Andrew, Beilfuss, Stefanie, Rudolph, Grit, Pommerening, Elke, Vos, Adriaan, Neubert, Andreas, Jahrling, Peter, Blaney, Joseph E., Johnson, Reed F., Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564550/
https://ncbi.nlm.nih.gov/pubmed/26063224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv251
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