Antibody Quality and Protection from Lethal Ebola Virus Challenge in Nonhuman Primates Immunized with Rabies Virus Based Bivalent Vaccine

We have previously described the generation of a novel Ebola virus (EBOV) vaccine platform based on (a) replication-competent rabies virus (RABV), (b) replication-deficient RABV, or (c) chemically inactivated RABV expressing EBOV glycoprotein (GP). Mouse studies demonstrated safety, immunogenicity,...

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Detalhes bibliográficos
Main Authors: Blaney, Joseph E., Marzi, Andrea, Willet, Mallory, Papaneri, Amy B., Wirblich, Christoph, Feldmann, Friederike, Holbrook, Michael, Jahrling, Peter, Feldmann, Heinz, Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667758/
https://ncbi.nlm.nih.gov/pubmed/23737747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003389
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