Preclinical Development of Inactivated Rabies Virus–Based Polyvalent Vaccine Against Rabies and Filoviruses

We previously described the generation of a novel Ebola virus (EBOV) vaccine based on inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) incorporated in the RABV virion. Our results demonstrated safety, immunogenicity, and protective efficacy in mice and nonhuman primates (NHPs). Prot...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Willet, Mallory, Kurup, Drishya, Papaneri, Amy, Wirblich, Christoph, Hooper, Jay W., Kwilas, Steve A., Keshwara, Rohan, Hudacek, Andrew, Beilfuss, Stefanie, Rudolph, Grit, Pommerening, Elke, Vos, Adriaan, Neubert, Andreas, Jahrling, Peter, Blaney, Joseph E., Johnson, Reed F., Schnell, Matthias J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564550/
https://ncbi.nlm.nih.gov/pubmed/26063224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv251
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