Preclinical Development of Inactivated Rabies Virus–Based Polyvalent Vaccine Against Rabies and Filoviruses

We previously described the generation of a novel Ebola virus (EBOV) vaccine based on inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) incorporated in the RABV virion. Our results demonstrated safety, immunogenicity, and protective efficacy in mice and nonhuman primates (NHPs). Prot...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Willet, Mallory, Kurup, Drishya, Papaneri, Amy, Wirblich, Christoph, Hooper, Jay W., Kwilas, Steve A., Keshwara, Rohan, Hudacek, Andrew, Beilfuss, Stefanie, Rudolph, Grit, Pommerening, Elke, Vos, Adriaan, Neubert, Andreas, Jahrling, Peter, Blaney, Joseph E., Johnson, Reed F., Schnell, Matthias J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564550/
https://ncbi.nlm.nih.gov/pubmed/26063224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv251
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