Preclinical Development of Inactivated Rabies Virus–Based Polyvalent Vaccine Against Rabies and Filoviruses

We previously described the generation of a novel Ebola virus (EBOV) vaccine based on inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) incorporated in the RABV virion. Our results demonstrated safety, immunogenicity, and protective efficacy in mice and nonhuman primates (NHPs). Prot...

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Vydáno v:J Infect Dis
Hlavní autoři: Willet, Mallory, Kurup, Drishya, Papaneri, Amy, Wirblich, Christoph, Hooper, Jay W., Kwilas, Steve A., Keshwara, Rohan, Hudacek, Andrew, Beilfuss, Stefanie, Rudolph, Grit, Pommerening, Elke, Vos, Adriaan, Neubert, Andreas, Jahrling, Peter, Blaney, Joseph E., Johnson, Reed F., Schnell, Matthias J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564550/
https://ncbi.nlm.nih.gov/pubmed/26063224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv251
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