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A potential link between insulin signaling and GLUT4 translocation: association of Rab10-GTP with the exocyst subunit Exoc6/6b

Insulin increases glucose transport in fat and muscle cells by stimulating the exocytosis of specialized vesicles containing the glucose transporter GLUT4. This process, which is referred to as GLUT4 translocation, increases the amount of GLUT4 at the cell surface. Previous studies have provided evi...

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Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Sano, Hiroyuki, Peck, Grantley R., Blachon, Stephanie, Lienhard, Gustav E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564306/
https://ncbi.nlm.nih.gov/pubmed/26299925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.08.069
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