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Clustered Tn-Antigen Mimetic-Based Cancer Therapeutic Vaccine Induces Strong Antibody-Mediated Protective Immunity
Tumor-associated carbohydrate antigens (TACAs) are key components of cancer vaccines. A variety of “native” TACA-based vaccines have shown immunogenicity and protection in pre-clinical animal studies, however the weak immunogenicity, in vivo instability and poor bioavailability, have discouraged the...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564297/ https://ncbi.nlm.nih.gov/pubmed/25168881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201406897 |
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