Clustered Tn-Antigen Mimetic-Based Cancer Therapeutic Vaccine Induces Strong Antibody-Mediated Protective Immunity

Tumor-associated carbohydrate antigens (TACAs) are key components of cancer vaccines. A variety of “native” TACA-based vaccines have shown immunogenicity and protection in pre-clinical animal studies, however the weak immunogenicity, in vivo instability and poor bioavailability, have discouraged the...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Richichi, Barbara, Thomas, Baptiste, Fiore, Michele, Bosco, Rosa, Qureshi, Huma, Nativi, Cristina, Renaudet, Olivier, BenMohamed, Lbachir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564297/
https://ncbi.nlm.nih.gov/pubmed/25168881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201406897
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