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Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) are key events in the development of artery restenosis following percutaneous coronary intervention. Digoxin has long been used in the treatment of heart failure and has been shown to inhibit the proliferation of cance...

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Détails bibliographiques
Publié dans:Int J Mol Med
Auteurs principaux: YAN, GAOLIANG, WANG, QINGJIE, HU, SHENGDA, WANG, DONG, QIAO, YONG, MA, GENSHAN, TANG, CHENGCHUN, GU, YUCHUN
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564091/
https://ncbi.nlm.nih.gov/pubmed/26311435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2320
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