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A novel PDGF receptor inhibitor-eluting stent attenuates in-stent neointima formation in a rabbit carotid model
A novel drug-eluting stent (DES) is required to target vascular smooth muscle cells (SMCs) without harming endothelial cells (ECs). Platelet-derived growth factor (PDGF) is critical for the proliferation and migration of SMCs. Sunitinib [a PDGF receptor (PDGFR) tyrosine kinase inhibitor]-eluting ste...
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| Опубликовано в: : | Mol Med Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355735/ https://ncbi.nlm.nih.gov/pubmed/27922693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5986 |
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