Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits

BACKGROUND: The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (6-MP) has been shown to have beneficia...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ruiter, Matthijs S., van Tiel, Claudia M., Doornbos, Albert, Marinković, Goran, Strang, Aart C., Attevelt, Nico J. M., de Waard, Vivian, de Winter, Robbert J., Steendam, Rob, de Vries, Carlie J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577071/
https://ncbi.nlm.nih.gov/pubmed/26389595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138459
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