Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits

BACKGROUND: The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (6-MP) has been shown to have beneficia...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Ruiter, Matthijs S., van Tiel, Claudia M., Doornbos, Albert, Marinković, Goran, Strang, Aart C., Attevelt, Nico J. M., de Waard, Vivian, de Winter, Robbert J., Steendam, Rob, de Vries, Carlie J. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577071/
https://ncbi.nlm.nih.gov/pubmed/26389595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138459
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