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Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) are key events in the development of artery restenosis following percutaneous coronary intervention. Digoxin has long been used in the treatment of heart failure and has been shown to inhibit the proliferation of cance...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: YAN, GAOLIANG, WANG, QINGJIE, HU, SHENGDA, WANG, DONG, QIAO, YONG, MA, GENSHAN, TANG, CHENGCHUN, GU, YUCHUN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564091/
https://ncbi.nlm.nih.gov/pubmed/26311435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2320
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