Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

The mechanism by which angiogenic endothelial cells break the physical barrier of the vascular basement membrane and consequently sprout to form new vessels in mature tissues is unclear. Here, we show that the angiogenic endothelium is characterized by the presence of functional podosome rosettes. T...

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Publicat a:Nat Cell Biol
Autors principals: Seano, Giorgio, Chiaverina, Giulia, Gagliardi, Paolo Armando, Blasio, Laura di, Puliafito, Alberto, Bouvard, Claire, Sessa, Roberto, Tarone, Guido, Sorokin, Lydia, Helley, Dominique, Jain, Rakesh K., Serini, Guido, Bussolino, Federico, Primo, Luca
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564017/
https://ncbi.nlm.nih.gov/pubmed/25218639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3036
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