Deep, Quantitative Coverage of the Lysine Acetylome Using Novel Anti-acetyl-lysine Antibodies and an Optimized Proteomic Workflow

Introduction of antibodies specific for acetylated lysine has significantly improved the detection of endogenous acetylation sites by mass spectrometry. Here, we describe a new, commercially available mixture of anti-lysine acetylation (Kac) antibodies and show its utility for in-depth profiling of...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Svinkina, Tanya, Gu, Hongbo, Silva, Jeffrey C., Mertins, Philipp, Qiao, Jana, Fereshetian, Shaunt, Jaffe, Jacob D., Kuhn, Eric, Udeshi, Namrata D., Carr, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Special Issue Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563726/
https://ncbi.nlm.nih.gov/pubmed/25953088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.047555
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