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New immunotherapies targeting the PD-1 pathway
Ligands from the B7 family bind to receptors of the CD28 family, which regulate early T cell activation in lymphoid organs and control inflammation and autoimmunity in peripheral tissues. PD-1, a member of the CD28 family, is an inhibitory receptor on T cells and is responsible for their dysfunction...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562806/ https://ncbi.nlm.nih.gov/pubmed/26162965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.06.005 |
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