A carregar...

The identification of an integral membrane, cytochrome c urate oxidase completes the catalytic repertoire of a therapeutic enzyme

In living organisms, the conversion of urate into allantoin requires three consecutive enzymes. The pathway was lost in hominid, predisposing humans to hyperuricemia and gout. Among other species, the genomic distribution of the two last enzymes of the pathway is wider than that of urate oxidase (Uo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Doniselli, Nicola, Monzeglio, Enrico, Dal Palù, Alessandro, Merli, Angelo, Percudani, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562309/
https://ncbi.nlm.nih.gov/pubmed/26349049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!