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Genetic Modifiers of Sickle Cell Disease

Sickle cell anemia is associated with unusual clinical heterogeneity for a Mendelian disorder. Fetal hemoglobin concentration and coincident ∝ thalassemia, both which directly affect the sickle erythrocyte, are the major modulators of the phenotype of disease. Understanding the genetics underlying t...

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Bibliografiske detaljer
Udgivet i:Am J Hematol
Main Authors: Steinberg, Martin H., Sebastiani, Paola
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562292/
https://ncbi.nlm.nih.gov/pubmed/22641398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23232
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