Development of Nonaggregating Poly-A Tailed Immunostimulatory A/D Type CpG Oligodeoxynucleotides Applicable for Clinical Use

Immunostimulatory CpG ODNs have been developed and utilized as TLR9-dependent innate immune activators and vaccine adjuvants. Four different types of immunostimulatory CpG ODNs (A/D, B/K, C, and P type) have been reported. A/D type ODNs are characterized by high IFN-α production but intrinsically fo...

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Pubblicato in:J Immunol Res
Autori principali: Aoshi, Taiki, Haseda, Yasunari, Kobiyama, Kouji, Narita, Hirotaka, Sato, Hideaki, Nankai, Hirokazu, Mochizuki, Shinichi, Sakurai, Kazuo, Katakai, Yuko, Yasutomi, Yasuhiro, Kuroda, Etsushi, Coban, Cevayir, Ishii, Ken J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562176/
https://ncbi.nlm.nih.gov/pubmed/26380317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/316364
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