Population Pharmacokinetic Model Characterizing 24-Hour Variation in the Pharmacokinetics of Oral and Intravenous Midazolam in Healthy Volunteers

Daily rhythms in physiology may affect the pharmacokinetics of a drug. The aim of this study was to evaluate 24-hour variation in the pharmacokinetics of the CYP3A substrate midazolam. Oral (2 mg) and intravenous (1 mg) midazolam was administered at six timepoints throughout the 24-hour period in 12...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:CPT Pharmacometrics Syst Pharmacol
मुख्य लेखकों: van Rongen, A, Kervezee, L, Brill, MJE, van Meir, H, den Hartigh, J, Guchelaar, H-J, Meijer, JH, Burggraaf, J, van Oosterhout, F
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley & Sons, Ltd 2015
विषय:
Original Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562161/
https://ncbi.nlm.nih.gov/pubmed/26380154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12007
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन