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LKB1 gene inactivation does not sensitize non-small cell lung cancer cells to mTOR inhibitors in vitro

AIM: Previous study has shown that endometrial cancers with LKB1 inactivation are highly responsive to mTOR inhibitors. In this study we examined the effect of LKB1 gene status on mTOR inhibitor responses in non-small cell lung cancer (NSCLC) cells. METHODS: Lung cancer cell lines Calu-1, H460, H129...

詳細記述

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書誌詳細
出版年:Acta Pharmacol Sin
主要な著者: Xiao, Ping, Sun, Lin-lin, Wang, Jing, Han, Rui-li, Ma, Qing, Zhong, Dian-sheng
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561965/
https://ncbi.nlm.nih.gov/pubmed/26027660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.19
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