Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy

Endometrial cancer – the most common malignancy of the female reproductive tract – arises from the specialized epithelial cells that line the inner surface of the uterus. Although significant advances have been made in our understanding of this disease in recent years, one significant limitation has...

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Detalhes bibliográficos
Main Authors: Contreras, Cristina M., Akbay, Esra A., Gallardo, Teresa D., Haynie, J. Marshall, Sharma, Sreenath, Tagao, Osamu, Bardeesy, Nabeel, Takahashi, Masaya, Settleman, Jeff, Wong, Kwok-Kin, Castrillon, Diego H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869492/
https://ncbi.nlm.nih.gov/pubmed/20142330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.004440
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