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The LKB1 Tumor Suppressor as a Biomarker in Mouse and Human Tissues
Germline mutations in the LKB1 gene (also known as STK11) cause the Peutz-Jeghers Syndrome, and somatic loss of LKB1 has emerged as causal event in a wide range of human malignancies, including melanoma, lung cancer, and cervical cancer. The LKB1 protein is a serine-threonine kinase that phosphoryla...
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| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783464/ https://ncbi.nlm.nih.gov/pubmed/24086281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073449 |
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