LKB1 gene inactivation does not sensitize non-small cell lung cancer cells to mTOR inhibitors in vitro

AIM: Previous study has shown that endometrial cancers with LKB1 inactivation are highly responsive to mTOR inhibitors. In this study we examined the effect of LKB1 gene status on mTOR inhibitor responses in non-small cell lung cancer (NSCLC) cells. METHODS: Lung cancer cell lines Calu-1, H460, H129...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Xiao, Ping, Sun, Lin-lin, Wang, Jing, Han, Rui-li, Ma, Qing, Zhong, Dian-sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561965/
https://ncbi.nlm.nih.gov/pubmed/26027660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.19
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