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ALS mutations in TLS/FUS disrupt target gene expression

Amyotrophic lateral sclerosis (ALS) is caused by mutations in a number of genes, including the gene encoding the RNA/DNA-binding protein translocated in liposarcoma or fused in sarcoma (TLS/FUS or FUS). Previously, we identified a number of FUS target genes, among them MECP2. To investigate how ALS...

詳細記述

保存先:
書誌詳細
出版年:Genes Dev
主要な著者: Coady, Tristan H., Manley, James L.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561479/
https://ncbi.nlm.nih.gov/pubmed/26251528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.267286.115
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