Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model

BACKGROUND: Members of the Eph/ephrin gene families act as key regulators of cerebellar development during embryogenesis. Aberrant signaling of Eph family of receptor tyrosine kinases and their ephrin ligands has also been implicated in human cancers. Medulloblastoma is an aggressive primitive neuro...

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Udgivet i:J Hematol Oncol
Main Authors: Bhatia, Shilpa, Hirsch, Kellen, Baig, Nimrah A., Rodriguez, Olga, Timofeeva, Olga, Kavanagh, Kevin, Lee, Yi Chien, Wang, Xiao-Jing, Albanese, Christopher, Karam, Sana D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Rapid Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561476/
https://ncbi.nlm.nih.gov/pubmed/26345456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0202-9
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