Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model

BACKGROUND: Members of the Eph/ephrin gene families act as key regulators of cerebellar development during embryogenesis. Aberrant signaling of Eph family of receptor tyrosine kinases and their ephrin ligands has also been implicated in human cancers. Medulloblastoma is an aggressive primitive neuro...

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Dettagli Bibliografici
Pubblicato in:J Hematol Oncol
Autori principali: Bhatia, Shilpa, Hirsch, Kellen, Baig, Nimrah A., Rodriguez, Olga, Timofeeva, Olga, Kavanagh, Kevin, Lee, Yi Chien, Wang, Xiao-Jing, Albanese, Christopher, Karam, Sana D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Rapid Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561476/
https://ncbi.nlm.nih.gov/pubmed/26345456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0202-9
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