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Roles of Collecting Duct Renin and (Pro)renin Receptor in Hypertension

In angiotensin (Ang) II-dependent hypertension, collecting duct renin synthesis and secretion are stimulated despite suppression of juxtaglomerular (JG) renin. This effect is mediated by Ang II type 1 (AT1) receptor independent of blood pressure. Although the regulation of JG renin is known, the mec...

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Bibliographic Details
Published in:Ther Adv Cardiovasc Dis
Main Authors: Gonzalez, Alexis A., Prieto, Minolfa C.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560657/
https://ncbi.nlm.nih.gov/pubmed/25780059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753944715574817
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