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The Replacement of 10 Non-Conserved Residues in the Core Protein of JFH-1 Hepatitis C Virus Improves Its Assembly and Secretion

Hepatitis C virus (HCV) assembly is still poorly understood. It is thought that trafficking of the HCV core protein to the lipid droplet (LD) surface is essential for its multimerization and association with newly synthesized HCV RNA to form the viral nucleocapsid. We carried out a mapping analysis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Etienne, Loïc, Blanchard, Emmanuelle, Boyer, Audrey, Desvignes, Virginie, Gaillard, Julien, Meunier, Jean-Christophe, Roingeard, Philippe, Hourioux, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560444/
https://ncbi.nlm.nih.gov/pubmed/26339783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137182
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