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The genotype 3‐specific hepatitis C virus core protein residue phenylalanine 164 increases steatosis in an in vitro cellular model

BACKGROUND AND AIMS: The prevalence and severity of liver steatosis are higher in patients infected with genotype 3 hepatitis C virus (HCV) than in patients infected with other genotypes. HCV core protein is known to affect lipid metabolism, inducing lipid droplet accumulation both in vitro and in v...

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Detalhes bibliográficos
Main Authors: Hourioux, C, Patient, R, Morin, A, Blanchard, E, Moreau, A, Trassard, S, Giraudeau, B, Roingeard, P
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267372/
https://ncbi.nlm.nih.gov/pubmed/17213339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.108647
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