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Core protein cleavage by signal peptide peptidase is required for hepatitis C virus-like particle assembly

Hepatitis C virus (HCV) core protein, expressed with a Semliki forest virus (SFV) replicon, self-assembles into HCV-like particles (HCV-LP) at the endoplasmic reticulum (ER) membrane, providing an opportunity to study HCV assembly and morphogenesis by electron microscopy. We used this model to inves...

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Detalhes bibliográficos
Main Authors: Ait-Goughoulte, Malika, Hourioux, Christophe, Patient, Romuald, Trassard, Sylvie, Brand, Denys, Roingeard, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Society For General Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2220033/
https://ncbi.nlm.nih.gov/pubmed/16528035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.81664-0
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