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Core protein cleavage by signal peptide peptidase is required for hepatitis C virus-like particle assembly
Hepatitis C virus (HCV) core protein, expressed with a Semliki forest virus (SFV) replicon, self-assembles into HCV-like particles (HCV-LP) at the endoplasmic reticulum (ER) membrane, providing an opportunity to study HCV assembly and morphogenesis by electron microscopy. We used this model to inves...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society For General Microbiology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2220033/ https://ncbi.nlm.nih.gov/pubmed/16528035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.81664-0 |
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