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Combined 2-deoxy glucose and metformin improves therapeutic efficacy of sodium-iodide symporter-mediated targeted radioiodine therapy in breast cancer cells

Radiosensitization using either metformin or 2-deoxy-d-glucose (2-DG) in various cancer cells has been reported. The present study reveals novel information on combining these drugs to enhance radiosensitization effect in breast cancer (BC) cells. Responses to low-dose Cobalt60 radiation, as well as...

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Bibliografiske detaljer
Udgivet i:Breast Cancer (Dove Med Press)
Main Authors: Chatterjee, Sushmita, Thaker, Nirmal, De, Abhijit
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560438/
https://ncbi.nlm.nih.gov/pubmed/26355636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S84648
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