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Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition

Vascular smooth muscle cells (VSMCs) undergo transcriptionally regulated reversible differentiation in growing and injured blood vessels. This de-differentiation also contributes to VSMC hyperplasia following vascular injury, including that caused by angioplasty and stenting. Stents provide mechanic...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Xie, Yi, Jin, Yu, Merenick, Bethany L., Ding, Min, Fetalvero, Kristina M., Wagner, Robert J., Mai, Alice, Gleim, Scott, Tucker, David, Birnbaum, Morris J., Ballif, Bryan A., Luciano, Amelia K., Sessa, William C., Rzucidlo, Eva M., Powell, Richard J., Hou, Lin, Zhao, Hongyu, Hwa, John, Yu, Jun, Martin, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560350/
https://ncbi.nlm.nih.gov/pubmed/25969542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005482
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