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CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells
CCR5 is a chemokine receptor expressed on leukocytes and a coreceptor used by HIV-1 to enter CD4(+) T lymphocytes and macrophages. Stimulation of CCR5 by chemokines triggers internalization of chemokine-bound CCR5 molecules in a process called down-modulation, which contributes to the anti-HIV activ...
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| Publié dans: | J Leukoc Biol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Leukocyte Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560160/ https://ncbi.nlm.nih.gov/pubmed/25957306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0414-193RR |
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