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A degradatory fate for CCR4 suggests a primary role in Th2 inflammation
CCR4 is the sole receptor for the chemokines CCL22 and CCL17. Clinical studies of asthmatic airways have shown levels of both ligands and CCR4(+) Th2 cells to be elevated, suggestive of a role in disease. Consequently, CCR4 has aroused much interest as a potential therapeutic target and an understan...
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| Publicado no: | J Leukoc Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155072/ https://ncbi.nlm.nih.gov/pubmed/32052476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.2A0120-089RR |
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