ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development

Biomarkers for predicting prognosis are critical to treating colorectal cancer (CRC) patients. We found that CSN6, a subunit of COP9 signalosome, is overexpressed in CRC samples and that CSN6 overexpression is correlated with poor patient survival. Mechanistic studies revealed that CSN6 is deregulat...

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Publicat a:Cancer Cell
Autors principals: Fang, Lekun, Lu, Weisi, Choi, Hyun Ho, Yeung, Sai-ching J., Tung, Jung-Yu, Hsiao, Chwan-Deng, Fuentes-Mattei, Enrique, Menter, David, Wang, Lei, Chen, Chuangqi, Wang, Jianping, Lee, Mong-Hong
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560098/
https://ncbi.nlm.nih.gov/pubmed/26267535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.07.004
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