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ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development
Biomarkers for predicting prognosis are critical to treating colorectal cancer (CRC) patients. We found that CSN6, a subunit of COP9 signalosome, is overexpressed in CRC samples and that CSN6 overexpression is correlated with poor patient survival. Mechanistic studies revealed that CSN6 is deregulat...
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| Veröffentlicht in: | Cancer Cell |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560098/ https://ncbi.nlm.nih.gov/pubmed/26267535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.07.004 |
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