Safety and Immunogenicity of a Dengue Virus Serotype-1 Purified-Inactivated Vaccine: Results of a Phase 1 Clinical Trial

We describe the results from a human clinical trial of a dengue virus serotype-1, purified-inactivated vaccine (DENV-1 PIV) adjuvanted with aluminum hydroxide. This first-in-man, Phase 1, open-label clinical trial consisted of two groups of flavivirus-naïve healthy adult volunteers that received two...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Martinez, Luis Javier, Lin, Leyi, Blaylock, Jason M., Lyons, Arthur G., Bauer, Kristen M., De La Barrera, Rafael, Simmons, Monika, Jarman, Richard G., Currier, Jeffrey R., Friberg, Heather, Danko, Janine R., Teneza-Mora, Nimfa C., Putnak, J. Robert, Eckels, Kenneth H., Thomas, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559679/
https://ncbi.nlm.nih.gov/pubmed/26149862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.14-0819
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