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The Effect of Bi-Terminal PEGylation of an Integrin α(v)β(6)–Targeted (18)F Peptide on Pharmacokinetics and Tumor Uptake

Radiotracers based on the peptide A20FMDV2 selectively target the cell surface receptor integrin α(v)β(6). This integrin has been identified as a prognostic indicator correlating with the severity of disease for several challenging malignancies. In previous studies of A20FMDV2 peptides labeled with...

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Detalles Bibliográficos
Publicado en:J Nucl Med
Autores principales: Hausner, Sven H., Bauer, Nadine, Hu, Lina Y., Knight, Leah M., Sutcliffe, Julie L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559355/
https://ncbi.nlm.nih.gov/pubmed/25814519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.150680
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