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The Effects of an Albumin Binding Moietyon the Targeting and Pharmacokinetics of an Integrin α(v)β(6)-Selective Peptide Labeledwith Aluminum [(18)F]Fluoride

PURPOSE: The α(v)β(6)-BP peptide selectively targets the integrin α(v)β(6), a cell surface receptor recognized as a prognostic indicator for several challenging malignancies. Given that the 4-[(18)F] fluorobenzoyl (FBA)-labeled peptide is a promising PET imaging agent, radiolabeling via aluminum [(1...

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Publicado en:Mol Imaging Biol
Main Authors: Hausner, Sven H., Bauer, Nadine, Davis, Ryan A., Ganguly, Tanushree, Tang, Sarah Y. C., Sutcliffe, Julie L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7647958/
https://ncbi.nlm.nih.gov/pubmed/32383076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01500-0
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