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The Effect of Bi-Terminal PEGylation of an Integrin α(v)β(6)–Targeted (18)F Peptide on Pharmacokinetics and Tumor Uptake

Radiotracers based on the peptide A20FMDV2 selectively target the cell surface receptor integrin α(v)β(6). This integrin has been identified as a prognostic indicator correlating with the severity of disease for several challenging malignancies. In previous studies of A20FMDV2 peptides labeled with...

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Bibliografski detalji
Izdano u:J Nucl Med
Glavni autori: Hausner, Sven H., Bauer, Nadine, Hu, Lina Y., Knight, Leah M., Sutcliffe, Julie L.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559355/
https://ncbi.nlm.nih.gov/pubmed/25814519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.150680
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