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Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors

BACKGROUND: Monoclonal antibodies have been used to effectively treat various tumors. We previously established a unique strategy to identify tumor specific antibodies by capturing B-cell response against breast tumor antigens from patient-derived sentinel lymph nodes. Initial application of this ap...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Devarakonda, Charan V., Kita, Daniel, Phoenix, Kathryn N., Claffey, Kevin P.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559304/
https://ncbi.nlm.nih.gov/pubmed/26334999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1608-z
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