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Potent enzyme inhibitors derived from dromedary heavy-chain antibodies.

Evidence is provided that dromedary heavy-chain antibodies, in vivo-matured in the absence of light chains, are a unique source of inhibitory antibodies. After immunization of a dromedary with bovine erythrocyte carbonic anhydrase and porcine pancreatic alpha-amylase, it was demonstrated that a cons...

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Hlavní autoři: Lauwereys, M, Arbabi Ghahroudi, M, Desmyter, A, Kinne, J, Hölzer, W, De Genst, E, Wyns, L, Muyldermans, S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170688/
https://ncbi.nlm.nih.gov/pubmed/9649422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.13.3512
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