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Specific Alu elements involved in a significant percentage of copy number variations of the STK11 gene in patients with Peutz–Jeghers syndrome

Peutz–Jeghers syndrome (PJS) is a rare hereditary syndrome characterized by the occurrence of hamartomatous polyps in the gastrointestinal tract, mucocutaneous pigmentation and increased risk of cancer in multiple internal organs. PJS is preconditioned by the manifestation of mutations in the STK11...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Fam Cancer
Hauptverfasser: Borun, Pawel, De Rosa, Marina, Nedoszytko, Boguslaw, Walkowiak, Jaroslaw, Plawski, Andrzej
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559094/
https://ncbi.nlm.nih.gov/pubmed/25841653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9800-5
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