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EMSAR: estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering

BACKGROUND: RNA-seq has been widely used for genome-wide expression profiling. RNA-seq data typically consists of tens of millions of short sequenced reads from different transcripts. However, due to sequence similarity among genes and among isoforms, the source of a given read is often ambiguous. E...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Lee, Soohyun, Seo, Chae Hwa, Alver, Burak Han, Lee, Sanghyuk, Park, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559005/
https://ncbi.nlm.nih.gov/pubmed/26335049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0704-z
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