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Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data

Alternative splicing leverages genomic content by allowing the synthesis of multiple transcripts and, by implication, protein isoforms, from a single gene. However, estimating the abundance of transcripts produced in a given tissue from short sequencing reads is difficult and can result in both the...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Newman, Jeremy R. B., Concannon, Patrick, Tardaguila, Manuel, Conesa, Ana, McIntyre, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118309/
https://ncbi.nlm.nih.gov/pubmed/30021829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200373
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