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Accurate quantification of transcriptome from RNA-Seq data by effective length normalization
We propose a novel, efficient and intuitive approach of estimating mRNA abundances from the whole transcriptome shotgun sequencing (RNA-Seq) data. Our method, NEUMA (Normalization by Expected Uniquely Mappable Area), is based on effective length normalization using uniquely mappable areas of gene an...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025570/ https://ncbi.nlm.nih.gov/pubmed/21059678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1015 |
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