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Duration of α(1)-antichymotrypsin gene activation by IL-1 is determined by efficiency of IkBα resynthesis in primary human astrocytes

Expression of α(1)antichymotrypsin (ACT) is significantly activated by IL-1 in human astrocytes; however, it is barely affected by IL-1 in hepatocytes. This tissue-specific regulation depends upon an enhancer which contains both NF-κB and AP-1 elements, and is also observed for an NF-κB reporter but...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurochem
Egile Nagusiak: Kiss, Daniel L., Xu, Weili, Gopalan, Sunita, Buzanowska, Katarzyna, Wilczynska, Katarzyna M., Rydel, Russell E., Kordula, Tomasz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558886/
https://ncbi.nlm.nih.gov/pubmed/15686474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2004.02900.x
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