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Mechanism of Interleukin-1- and Tumor Necrosis Factor α-Dependent Regulation of the α(1)-Antichymotrypsin Gene in Human Astrocytes
The expression of α(1)-antichymotrypsin (ACT) is significantly enhanced in affected brain regions in Alzheimer's disease. This serine proteinase inhibitor specifically colocalizes with filamentous β-amyloid deposits and recently has been shown to influence both formation and destabilization of...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772857/ https://ncbi.nlm.nih.gov/pubmed/11027208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-20-07510.2000 |
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