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Duration of α(1)-antichymotrypsin gene activation by IL-1 is determined by efficiency of IkBα resynthesis in primary human astrocytes
Expression of α(1)antichymotrypsin (ACT) is significantly activated by IL-1 in human astrocytes; however, it is barely affected by IL-1 in hepatocytes. This tissue-specific regulation depends upon an enhancer which contains both NF-κB and AP-1 elements, and is also observed for an NF-κB reporter but...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558886/ https://ncbi.nlm.nih.gov/pubmed/15686474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2004.02900.x |
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