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FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β

Aberrant activation of Wnt/β-catenin signaling plays an unequivocal role in colorectal cancer, but identification of effective Wnt inhibitors for use in cancer remains a tremendous challenge. New insights into the regulation of this pathway could reveal new therapeutic point of intervention, therefo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Gao, Chenxi, Chen, Guangming, Kuan, Shih-Fan, Zhang, Dennis Han, Schlaepfer, David D, Hu, Jing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558782/
https://ncbi.nlm.nih.gov/pubmed/26274564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10072
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